HSAT2 and HERV-K Exosomal Biomarkers
The HSAT2/HERV-K exosomal hypothesis:hsat2-exosome-mdsc:hsat2-postviral-memory proposes a molecular mechanism for chronic ME/CFS immune suppression. If confirmed, it generates a specific set of measurable biomarkers that could stratify patients, guide treatment selection, and serve as pharmacodynamic endpoints in trials.